Statement(s) regarding ulcerative colitis | Crack PGIMER NOV 2016

Which of the following statement(s) regarding ulcerative colitis is/are correct? 

A. The most common age of onset for ulcerative colitis is in early adulthood 
B. Approximately 25% of cases of ulcerative colitis occur after the age of 60 
C. Males are affected approximately twice as frequently as females 
D. Approximately 10% to 25% of patients with ulcerative colitis have first degree relatives with the disease
E. all are true

The answer is. A. The most common age of onset for ulcerative colitis is in early adulthood

D. Approximately 10% to 25% of patients with ulcerative colitis have first degree relatives with the disease

Most cases of ulcerative colitis have onset between the ages of 15 and 40 years. While the age of onset may extend to old age, only 3% to 5% of the cases have onset after age 60. Males and females are affected equally frequently. Clear-cut familial patterns have been observed in ulcerative colitis. Ten to 25% of patients with this disease have first degree relatives with ulcerative colitis. Monozygotic twins have higher concordance for inflammatory bowel disease than dizygotic twins.