The interstitial lung diseases with a predilection for the upper lung zones include all of the following except-
A. Eosinophilic granuloma (histiocytosis X)B. Silicosis
C. Late stages of sarcoidosis
D. Idiopathic pulmonary fibrosis
E. Tuberculosis
Answer.
D. Idiopathic pulmonary fibrosis;
Most interstitial lung diseases have a predilection
for the lower lung zones, including idiopathic pulmonary fibrosis. However,
there are several diseases that tend to present predominantly in the upper lung
zones, including silicosis, berylliosis, coal worker's pneumoconiosis, cystic
fibrosis, eosinophilic granuloma, ankylosing spondylitis, nodular rheumatoid
arthritis, late stages of sarcoidosis, lymphangioleiomyomatosis, mycosis, Mycobacterium, and Pneumocystis carinii pneumonia (PCP)
found in AIDS patients who are on inhaled pentamidine prophylaxis. 