ACE inhibitors | PGI based MCQs

ACE inhibitors cause 

A. Persistent cough 
B. Taste changes 
C. First dose hypotension 
D. Ankle edema 
E. Angioedema

The Answer is. (A) Persistent cough ;(B) Taste changes; (C) First dose hypotension: (E) Angioedema:

• ACE inhibitors causes

— Persistent cough                              — Hyperkalemia, proteinuria

— Dysguesia due to captopril           — Granulocytopenia

— Anglo-edema                  — Rash, urticaria

— First dose hypotension — Fetotoxicity

• First dose hypotension is uncommon in Lorsartan, less common in Enalapril, Lisinopril.

• ActiveACE inhibitors (not converted to metabolite) are

— Captopril

— Lisinopril