Two specific tests to diagnose Wilson’s disease | PGI May 2017 Preparations MCQ

Two specific tests to diagnose Wilson’s disease are: 

A. KF ring 
B. Liver copper by dry weight of liver < 200 microgm/gm of dry weight 
C. Sr. Ceruloplasmin 
D. 24 hours urine copper after penicillamine 
E. Sr. copper

Ans. A. KF ring ; (C) Sr. Ceruloplasmin

The diagnosis of wilson’s disease is confirmed by demonstration of either
(i) Sr. Ceruloplasmin level <20 mg/dl and K.F. ring
(ii) Serum ceruloplasmin level <20 mg/dl and a concentration of copper in a liver biopsy sample >200 microgm/gm dry weight.
In the question, mentioned copper concentration 200 µgm/g dry wt. So, combined A, C will be the best choice.