Renal cell carcinoma histopathologicaly showing ‘perinuclear halo’ & “Plant like” structure in malignant cells
A. Clear cell tumorB.Adenocarcinoma
C. Collecting duct. Ca.
D. Oncocytoma
E. None
The Answer is. e.(None)
• The histopathological changes — “perinuclear halo”
‘Plant like’ is found in
chromophobe renal carcinoma.
Histopathological change of other renal cell carcinoma:
• Clear cell Carcinoma:Growthpattern varies from cord like to tubular
—Cells are polygonal or rounded with clear or granular
cytoplasm with glycogen and lipid.
— Solid as wall as cystic areas, have delicate branching
vasculature.
— Some have marked nuclear atypia with bizarre nuclei
and giant cells.
• Papillary :—
Papillary arrangement of cells
— Interstitial foam cells,Psamomma bodies
• Collecting duct Ca :aka bellini duct cancer / tubulocystic carcinoma. Has
strong association with the transitional cell carcinoma. Histology:bubble wrap appearance.
• Oncocytoma :Eosinophillic
cells with abuudant mitochondria.
