In hyperventilation
a. p50 and Hb affinity for 02 increasesb. p50 and Hb affinity for 02 decreases
c. p50 increases and 02 affinity decreases
d. p50 decreases and 02 affinity increases
e. no change
Ans: (D) p50 decreases and 02 affinity increases
• P50 is the partial pressure of Oxygen (Pa02), at which Hemoglobin is 50% saturated. The normal value is 26.6 mm of Hg. As the oxygen dissociation curve shifts toward left i.e. P50 decreases & 02 affinity increases when there is
hypocarbia due to hyperventilation.
