Friday, 5 February 2016

The effective renal plasma flow


The effective renal plasma flow, which equals the clearance of PAH, is less than the true renal plasma flow because:

A. The fraction of PAH filtered is less than the filtration fraction 
B. The plasma entering the renal vein contains a small amount of PAH
C. The cortical and medullary collecting ducts are able to reabsorb some PAH
D. The calculated clearance of PAH depends on the urinary flow rate

The Answer is B.  
The clearance of PAH equals the true renal plasma flow only if the kidney reabsorbs all of the filtered PAH, that is, no PAH appears in the renal vein. Because the kidney is only able to reabsorb approximately 85 to 90% of the filtered PAH, some PAH appears in the renal vein, and the PAH clearance is less than the true renal plasma flow.