Saturday, 14 January 2017

True about Fat absorption | PGI May 2017 Preparations


True about fat absorption 

A. Fat in stool > 6 gm/day indicate malabsorption 
B. C-glycine test is most sensitive test 
C. Major fat absorption occurs in proximal intestine 
D. Steatorrhea means stool fat> 10 gm/day 
E. Steatorrhea is increased fat in stools >20gm/day



Ans. A. Fat in stool > 6 gm/day indicate malabsorption:
(C) Major fat absorption occurs in proximal intestine :
·      Normal fecal fat excretion is less than 6gm/day, more than 6 gm/24 hr indicates malabsorption.
• Fat absorption takes place in small intestine except short chain fatty acids which is absorbed in colon
• Sudan is best for screening but gold standard is quantitative estimation of fecal fat. OraL glycin glycolate test may show bile acid malabsorption, but not best for screening.
- Steatorrhea is defined as stool fatexeeeding 7g/day
- Daily fecal averages 15-25 g with small intestine disease, often exceeds 40 gm with pancreatic disease.