Sunday, 15 January 2017

Use of timolol in the eye can cause | PGI May 2017 Preparations


Use of timolol in the eye can cause: 


A. AV block 
B. Bradycardia 
C. Hypertension 
D. Hypotension 
E. Asthma


Ans. A. AV block; (B) Bradycardia; (D) Hypotension; (E) Asthma :
On topical application of β-blocker on eye, there can occur significant systemic absorption, producing systemic adverse effects :
• Bronchospasm
• Accentuation of heart block
• Congestive heart failure especially in elderly
• Bradycardia
• Other adverse effects: depression, anxiety, confusion, drowsiness, loss of libido, skin rashes, diarrhoea, nausea.