The following should be avoided in suspected immunodeficiency:
A. MMRB. DPT
C. Oral polio vaccine
D. Pneumovax II vaccination
E. Transfusion of packed cells
The answer is. A. MMR, C.
Oral polio vaccine, E. Transfusion of packed cells
•Live vaccines:
MMR, oral polio, BCG, measles.
•Killed:
pertussis.
•Inactivated: IM
polio.
•Toxoids: DT.
•Submit: Hib.
Packed cells
contain a few lymphocytes which can givetransfusional graft versus hostdisease
(GVHD) in SCID, which is invariably fatal. Viruses canalso be transmitted
viablood products.
