Poor prognostic factors in the management of Cancer Cervix | NEET Based MCQs

Poor prognostic factors in the management of cancer cervix are the following except 

A. Young age 
B. Well-differentiated squamous cell carcinoma 
C. Hydroureter 
D. Adenocarcinoma

Answer: B (Well-differentiated squamous cell carcinoma)
Prognosis of carcinoma of the cervix:
1. Stage of lesion at the initial therapy (most important factor)

Stages	Survival rate (%)
I	85
II	55
Ill	3
IV	15

2. Endocervical tumor—diagnosed late and grows faster. (Adenocarcinoma develops from endocervical canal.)
3. Depth of tumor when <1 cm, less lymph nodes are involved and improved survival.
4. Tumor size >4 cm, associated with more lymph node metastasis and poor survival.
5. Well-differentiated squamous cell carcinoma grows slowly and metastasis late than the anaplastic type.
6. Young age is usually associated with poorly differentiated squamous cell carcinoma or adenocarcinoma and is prognostically poor

7. Lymph node involvement—pelvic and para-aortic reduces the survival rate by 50%.
8. HPV-positive younger patients have better prognosis