True regarding cancer colon
A. Obstructive features are more common with right colonB. 40% cases at presentation show liver metastasis
C. Resection possible in25% cases
D. More common in AIDS patients
E. mortality is as high as 60%
The Answer is. (B) 40% cases at presentation show liver metastasis
• Liver is the most common site of metastasis. Patient may present for the first time with liver
metastasis, It is involved in 2/3rd of cases at the time of death; and 1/3rd of
cases of recuring colorectal carcinoma.
• Patient with solitary liver metastasis with clinical or radiological evidence of additional tumour involvement should be considered for liver resection.
• Patient with solitary liver metastasis with clinical or radiological evidence of additional tumour involvement should be considered for liver resection.
• Anal Cancer risk is increased both in men and women with AIDS probably immunosuppression
permits more severe human parpilloma virus infection.
• Approx 20%
of pt’s have metastatic disease at the time of initial diagnosis and another
30% eventually develop metastasis. Long term survival is 55%. Resection of
isolated (1 to 3) liver or lung metastasis may result in long-term (5 years)
survival in 20-40% of cases.
• Combination therapy provides significant improvement
in tumour response rate (40%).
• Almost 90% of the patients have tumours that can be
resected completely and mortality rate ranges from 2% to 10%.
