Thursday 23 March 2017

Antiphospholipid antibody syndrome | Crack AIIMS, NEET 2017 with NIME MCQs


Antiphospholipid antibody syndrome is characterized by all of the following EXCEPT 

A. Recurrent abortions 
B. Arterial thrombosis 
C. Thrombocytopenia 
D. None of the above


Ans. D. (none) Explanation
• Individuals with the antiphospholipid antibody syndrome present with an extreme variety of clinical manifestations;
A. These are typically characterized by recurrent venous or arterial thrombi
B. Repeated miscarriages
C. Cardiac valvular vegetations
D. Thrombocytopenia
E. Venous thromboses occur most commonly in deep leg veins, but renal, hepatic, and retinal veins are also susceptible.
F. Arterial thromboses typically occur in the cerebral circulation, but coronary, mesenteric, and renal arterial occlusion have also been described.

G. Depending on the vascular bed involved, the clinical presentations can vary from pulmonary embolism (due to a low extremity venous thrombus), to pulmonary hypertension (from recurrent subclinical pulmonary emboli), to stroke bowel infarction, or renovascular hypertension.