Ferruginous bodies are seen in
A. SilicosisB. Asbestosis
C. Bagassosis
D. Byssinosis (lung)
Ans. B. (Asbestosis)
Explanation
• Asbestosis is marked by diffuse pulmonary interstitial fibrosis, which is indistinguishable from diffuse interstitial fibrosis resulting from other causes, except for the presence of asbestos bodies.
• Asbestosis is marked by diffuse pulmonary interstitial fibrosis, which is indistinguishable from diffuse interstitial fibrosis resulting from other causes, except for the presence of asbestos bodies.
•
Asbestos bodies appear as golden brown, fusiform or beaded rods with a
translucent center and consist of asbestos fibem coated with an iron-containing
proteinaceous material.
•
They arise when macrophages attempt to phagocytose asbestos fibers; the iron is
presumably derived from phagocyte ferritin.
• Other inorganic particulates may become coated
with similar iron protein complexes and are called ferruginous bodies. Sometimes
asbestos bodies can be found in the lungs of normal people, but usually in much
lower concentratioi and without interstitial fibrosis.
