Monday 21 September 2015

AIIMS MCQ for Medical PG Preparations .. NIME | lgrastim (G-CSF), sargramostim (GM-CSF) MCQ

Relative to filgrastim (G-CSF), sargramostim (GM-CSF)
A. Has greater oral bioavailability
B. Is more likely to causethrombocytopenia
C. Is more likely to elicit an allergic reaction
D. Stimulates production of a wider variety of hematopoietic stem cells



Ans. D. Stimulates production of a wider variety of hematopoietic stem cells
GM-CSF has wider biologic activity than G-CSF; it stimulates early myeloid stem cells in addition to cells destined become neutrophils