Reflux esophagitis is prevented by
A. Long intraabdominal esophagusB. Increased intraabdominal pressure
C. Right crus of diaphragm
D. Increased intrathoracic pressure
E. All of above
Answer (A) Long intraabdominal esophagus;
(C) Right
crus of diaphragm; 
(D) Increased intrathoracic pressure 
• The anti-reflux mechanisms are (GERD protective): 
— Lower esophageal splincter 
— Anatomic location of Gastroesophageal junction below
the diaphragmatic hiatus. 
— The crural diaphragm (rt crus). 
— The oblique entry, of Lower esophagus into stomach. 
— Gravity, intrathoracic pressure prevents reflux of
the gastric content to esophagus. 
• Reflux occurs when weakness of LES, high
intra-abdominal pressure, delayed gastric emptying, incr. gastric volume
Complications include — Esophagitis, peptic stricture,
and Barret’s esophagus. 
Reflux esophagitis best diagnosed by endoscopy also by
Ba Swallow, mucosal biopsy. 
24 hr pH
recording
is the Gold standard for diagnosis of GERD.