The drug of choice for the treatment of chlamydial infection is
A. AmpicillinB. Third generation cephalosporins
C. Metronidazole
D. Doxycycline
Answer:
D (Doxycycline)
Treatment of chlamydial infection
• Doxycycline or tetracycline:
o 7-day course for genital infections.
o 2-week course for complicated (PID, epididymis) chlamydial infections.
o 3-week course for LGV.
• Azithromycin—highly active against C. trachomatis, exhibits prolonged bioavailability, is concentrated intracellularly and single dose (1 g) therapy.
• Ofloxacin (300 mg BD for 7 days).
• Erythromycin base 500 mg QD for 10—14 days is regimen of choice for pregnant women.
• Amoxicillin (500 mg TDS for 10 days) has also been used successfully in pregnant women.
Treatment of chlamydial infection
• Doxycycline or tetracycline:
o 7-day course for genital infections.
o 2-week course for complicated (PID, epididymis) chlamydial infections.
o 3-week course for LGV.
• Azithromycin—highly active against C. trachomatis, exhibits prolonged bioavailability, is concentrated intracellularly and single dose (1 g) therapy.
• Ofloxacin (300 mg BD for 7 days).
• Erythromycin base 500 mg QD for 10—14 days is regimen of choice for pregnant women.
• Amoxicillin (500 mg TDS for 10 days) has also been used successfully in pregnant women.
