True about PNH | PGI based MCQs

True about PNH is/are :

A. Hypocellularmarrow
B. Budd-chairi syndrome 
C. Thrombosis 
D. LAP Score low
E. venous plasma leakage

The Answer is. (B) Budd-chiari syndrome; (C) Thrombosis; (D) LAP Score low

• Three common manifestations of PNH

— Hemolytic anemia (intravascular)

— Venous thrombosis

— Deficient haematopoiesis (pancytopenia)

•Bone marrow appears normocellular but in vitro marrow progenitor areabnormal in PNH.

• Budd-chiari syndrome is hepatic vein thrombosis can occur in PNH.

• LAP score is low.