Which of the following hormones interacts with a cytoplasmic receptor and then localizes in the nucleus and directs protein and nucleotide synthesis?
A. Thyrotropin – releasing hormoneB. Epinephrine
C. LH
D. Cortisol
The Answer is D Cortisol, like
other steroid hormones, diffuses into target cells and interacts with
intracellular receptors. The steroid-receptor complex has a high affinity for
the steroid- responsive element of DNA. Once bound to DNA, the hormone-receptor
complex acts as a transcription factor to regulate gene expression and
formation of specific messenger RNAs.
