Features of cystic fibrosis

Features of cystic fibrosis: 

a. Lung normal at birth 
b. Abnormal sweat chloride tests 
c. Autosomal dominant 
d. Defect in chromosome 11 
e. Associated with exocrine pan creative in sufficiency

Ans: (A) Lung normal at birth; (B) Abnormal sweat chloride test (E). Associated with exocrine pan creative in sufficiency

* Cystic fibrosis (CF) is an autosomal recessive disease, where all the exocrine glands in the body especially those in the respiratory & GIT system are involved & produce abnormal visid mucous. The gene is located on the chromosome-7.

* The diagnosis is confirmed by demonstration of a high sweat chloride (>60 mEqIL) on repeated measurements.

* Treatment – Respiratory care

- Nutritional care

- Anticipation & early diagnosis of liver disease, diabetes & other organ dysfunction.