Lesion in Wernicke’s encephalopathy occurs in
A. Mamillary bodyB. Cerebellum
C. Motor cortex
D. Substantia nigra
Ans. (a) Mammillary body
• Psychosis occur in Wernicke
Korsakoff syndrome secondary to thiamine deficiency. It is consistent with
pathologic changes in the cortex, cerebellum, and mammillary bodiesof the thalamus.
• Parenteral thiamine should be given prophylactically to all chronic
alcoholic patients in the emergency room, or as soon as they are admitted, to
prevent precipitation of thiamine deficiency after the provision of
glucose-containing solutions
