To diagnose hyperglycemia of two weeks old

To diagnose hyperglycemia of two weeks old the best investigation retrospectively is 

A. Ketone bodies 
B. Glycosated hemoglobin 
C. Glucose in the blood 
D. Chromosomal study


Ans. (b) Glycosylated HB
• Normal whole blood hemoglobin A₁ is approximately 4 to 6 percent of total hemoglobin; reflect the metabolic
• Control over the preceding 3 months,
• Hemoglobin A₁ may be falsely elevated in patients whose diabetes is unstable when the intermediate
• Precursor is elevated, e.g. in alcoholism and falsely lowered in conditions of shortened red blood cell lifespan, e.g. in anemia and acute or chronic blood loss or in patients with hemoglobinopathies, e.g. sickle cell disease.