Medical PG Preparations | Drug of choice for intraoperative right heart failure

Drug of choice for intraoperative right heart failure due to pulmonary hypertension? 

A. Dopamine
B. Isoprenaline
C. Milrinone 
D. Halothane

Ans. C. Milrinone.                

Drug of choice for intraoperative right heart failure due to pulmonary hypertension is Milrinone.

•PDEls cause significant peripheral and pulmonary vasodilatation, reducing afterload and preload, while increasing inotropy.

•These affects make them well suited for patients with LV dysfunction and pulmonary hypertension and posttransplant patients.

•Milrinone is renally excreted, necessitating dose adjustment in the presence of renal dysfunction or substitute with dobutamine.

•Milrinone has many side-effects, including marked hypotension PAC monitoring is recommended. , as well as atrial and ventricular arrhythmias.