Sunday, 19 March 2017

The two nitrogen atoms in urea arise from | Crack AIIMS, NEET 2017 MCQs


The two nitrogen atoms in urea arise from: 

A. Ammonia and glutamine 
B. Ammonia and asp artic acid 
C. Glutamine and glutamic add 
D. Glutamine and alanine





Ans. B. Ammonia and Aspartic acid                                                                               

Urea cycle  
• Takes place in liver and brain.
• 1st two reactions occur in mitochondria.
• 1st two reactions are rate controlling reactions.
• Nitrogen atoms arise from Ammonia and Aspartic acid
• Combination of “Hyperammonemia+ ‘t’Blood Glutaniine+4.Blood urea” suggests defect in Urea Cycle. Lethargy, vomiting, coma are associated.