Treatment of DI
A. ADHB. Thiazide
C. Loop diuretics
D. Insulin
E. Chlorpromazine
Ans.
A. ADH; (B) Thiazide
• Desmopressin (DDAVP = desamino-D-arginine-8 vasopressin) acetate is the treatment of choice for central diabetes insipidus. It is a synthetic analogue of AVP that acts selectively at V2 receptors to increase urine concentration and decrease urine flow in dose dependent manner. Lypressin or vasopressin are alternatives.
• Other drugs for DI.
Chlorpropamide for pituitary DI
— Thiazide diuretics for Nepbrogenic DI
— Carbamazipine reduced the urine volume in pituitary DI
— Clofibrate has shown beneficial for nephrogenic DI
— Indomethacin
• Desmopressin (DDAVP = desamino-D-arginine-8 vasopressin) acetate is the treatment of choice for central diabetes insipidus. It is a synthetic analogue of AVP that acts selectively at V2 receptors to increase urine concentration and decrease urine flow in dose dependent manner. Lypressin or vasopressin are alternatives.
• Other drugs for DI.
Chlorpropamide for pituitary DI
— Thiazide diuretics for Nepbrogenic DI
— Carbamazipine reduced the urine volume in pituitary DI
— Clofibrate has shown beneficial for nephrogenic DI
— Indomethacin
