Friday, 22 April 2016

Drug of choice for Methicillin resistant staphylococcus aureus | Crack PGIMER 22 MAY 2016


Drug of choice for Methicillin resistant staphylococcus aureus is (MRSA) 

A. Amoxicillin-Clavulanate
B. Vancomycin 
C. Flucloxacillin 
D. Clindamycin 
E. Erythromycin


The Answer is. (B) Vancomycin
• Vancomycin is the drug of choice of MRSA infections.
• Although sensitive strains may be amenable to therapy with clindamycin or trimethoprimsulfamethoxazole— but many strains are resistant to them.
• New antibiotic quinopristin/dalfopristin and linézolid offer promise for treatment of MRSA, further studies are needed for their recommendation
• Unfortunately, increased use of vancomycin has resulted in emergence of both Vancomycin- Intermediate S. Aureus (VISA), and Vancomycin resistant enterococci (VRE)
• Optimal therapy for VISA is unknown.

Note: Teicoplanin can aiso he used in MRSA infections