Friday 8 April 2016

Parafollicular ‘C’ cells | Crack PGIMER 22 MAY 2016


Parafollicular ‘C’ cells develop from 

A. Second branchial pouch 
B. Second branchial cleft 
C. Ultimobranchial body 
D. Third branchial pouch
E. First branchial pouch


The Answer is. (C) Ultimobronchial body:
Para follicular ‘C’ cells of thyroid develops from ultimobranchial body
High yield:
Thyroid gland: embryological clinical defects:
If the thyroglossal duct does not atrophy, then the remnant can manifest clinically as a thyroglossal duct cyst. If the cyst ruptures, it may go on to form a thyroglossal duct sinus or a thyroglossal duct fistula that exits through the overlying skin. Because the hyoid bone develops in an anterior direction and may surround the thyroglossal duct, the surgeon should resect the central portion on the hyoid bone along with the cyst (the Sistrunk procedure).
An aberrant or ectopic thyroid gland may occur anywhere along the path of initial descent of the thyroid, although it is most common at the base of the tongue, just posterior to the foramen cecum. In this location, an aberrant or ectopic thyroid gland is known as a lingual thyroid and represents a failure of the thyroid to descend

Accessory thyroid tissue can also occur, arising from remnants of the thyroglossal duct. While the accessory thyroid tissue may be functional, it is generally insufficient for normal function if the main thyroid gland is entirely removed. This accessory tissue may appear anywhere along the path of the thyroglossal duct tract