True about carcinoembryonic antigen (CEA)
A. Useful for screening of Ca. colonB. gives confirmative evidence of Ca. colon
C. Helpful for follow-up after resection
D. Levels decrease immediately after resection of tumor
E. Tumour mass size correlates with CEA level
The Answer is.
(A) Useful for screening of Ca. colon (C) Helpful
for follow up after resection (D)Levels
decrease immediately after resection of tumor
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CEA is usefull for screening of the some cancers, particularly colon cancer
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CEA is marker to monitor colorectal carcinoma treatment, to identify
recurrences after surgical resection, for staging or to localize cancer spread
through measurement of biological fluids.
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CEA levels may also be raised in gastric carcinoma, pancreatic carcinoma, lung
carcinoma, breast carcinoma, and medullary thyroid carcinoma, as well as some
non-neoplastic conditions like ulcerative colitis, pancreatitis,
cirrhosis,COPD, Crohn's disease, hypothyroidism.
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It varies inversely with tumor grade (well-differentiated tumors secrete more
CEA). CEA is elevated more in tumors with lymph node and distant metastasis
than in organ-confined tumors (varies directly with tumor stage). Also, Tumors
causing obstruction produce higher CEA levels.
