Skin pigmentation occurs with which of the following drugs
A. ClofazimineB. Minocycline
C. Sulfonamides
D. glucosamines
E. Gold
The Answer is. (A) Clofazimine; (B) Minocycline ;(E) Gold ;
• Pigmentary changes (skin) caused by drugs with their
appearance are given below
Note
|
Appearance
— Flat hyperpigmented areas
— Blue-black patches
— Blue-gray discoloration
|
Distribution
Forehead and cheeks (chloasma, melasma) on shins Light exposed areas |
Drugs
OCP Minocycline, chloroquine Chiorpromazine and related phenothiazines |
|
— Brown and blue-gray pigmentation Reddish black —
Slate-gray colour
— Yellow colour
|
Generalised
Sun exposed areas Photo exposed areas |
Heavy metals (Ag, Au. Bi, As)ClofazimineAmiodarone
|
* Chloroquine causes blue-black pigmentation of nails
arid palate and depigmentation of hair.
* Zidovudine, hydroxyurea causes brown discolouration
of nails.
* Sulphonamidecause fixed drug eruptions.
* Rifampicin cause redish discolouration of sweats.
* Vancomycin causeRedman Syndrome.
