HCL secretion is stimulated by
A. Secretin
B. Somatostatin
C. Histamine
D. Gastrin
E. VIP
The Answer
is (C) Histamine;(D) Gastrin
• Acid
secretion is stimulated by
— Histamine via H2-receptors
— Gastrin
— Acetylcholine M3 muscarinic receptors
• Factors that inhibit Gastric secretion are
— Enterogastric reflex
— Hormones e.g cholecystokinin, GIP, VIP and
somatostatin
— Presence of fat, acid, protein breakdown products,
hypo-or hyperosmotic fluids. any irritating factors in upper small intestine causes
release of these hormones
