Saturday, 19 September 2015

PGI MCQ for Medical PG Preparations .. NIME | enzyme reverse transcriptase MCQ

Reverse transcriptase is an enzyme unique to the retroviruses. Which one of the following is a function of the enzyme reverse transcriptase?
A. DNase activity
B. RNA-dependent RNA polymerase activity
C. RNA-isomerase activity
D. RNA- dependent DNA polymerase activity



Ans. D.
The replication of a retroviral genome is dependent on the reverse transcriptase enzyme, which performs a variety of functions. It builds a complementary strand of DNA for the viral RNA template.; it builds a second DNA stand complementary to the previous DNA; it degrades the original RNA, leaving a DNA-DNA duplex; and, finally, it is responsible for integrating  the new viral DNA hybrid into the host genome.