An 80-year-old, asymptomatic man presents with a total leucocyte count of 1 lakh, with 80% lymphocytes and 20% PMC’s. Most probably this patient is suffering from
A. AMLB. CML
C. CLL
D. TB
Ans. C. (CLL)
Explanation
In the question, following things are the reason for the diagnosis—age, 80 years; asymptomatic; gender—male; TLC—l lakh; lymphocytes 80%; with 20% PMCs.
In the question, following things are the reason for the diagnosis—age, 80 years; asymptomatic; gender—male; TLC—l lakh; lymphocytes 80%; with 20% PMCs.
In
CLL,following important points, we should know
• Median age—65 years
• Male percentage—53%
• Increased number of
circulating lymphocytes (i.e., >4 x 109/L and usually> 10 x 109/L) and same finding in bone marrow confirm the
diagnosis.
• Peripheral blood smear shows
many “smudge” or “basket” cells, nuclear remnants
of cells damaged by the physical shear stress.
• Trisomy 12 is found in 25% to 30% of patients.
• Typically, CLL is often found
incidently when a complete blood count is done for other reason.
