For which of the following disease, vaccine is contraindicated in pregnancy, even following maternal exposure?
A. RabieB. Measles
C. Typhoid
D. Hepatitis B
The answer is b.
Teratogenic
concerns regarding the vaccine must be weighed against the potential for harm
from the infectious agent. In the case of hepatitis A and B, rabies, tetanus,
and varicella, patients may be treated with hyperimmunoglobulin or pooled
immune serum globulin. Inactivated bacterial vaccines can be used for cholera,
plague, and typhoid as appropriate. Vaccines for measles and mumps are
generally considered to be contraindicated as these are live viruses,
although the rubella vaccine, which is known to have been administered
inadvertently to over 1000 pregnant women, has never caused a problem and in
fact can be used in selected circumstances of exposure.
