Wednesday, 22 November 2017

Hypocalcemia with hyperphosphatemia | PGI Nov 2017 Preparations MCQ


Hypocalcemia with hyperphosphatemia are seen in :

A. CRF 
B. Pseudohypoparathyoidsm
C. Vit-D deficiency 
D. Magnesium deficiency
E. Tumour lysis Syndrome



Answer. A. CRF ; (B) Pseudohypoparathyoidsm; (E) Tumour lysis Syndrome
Hypocalcemia with hyperphosphatemia is associated with :
— Chronicrenal failure.
— Pseudohypoparathyroiclism.
---- Albright’s  heriditary osteodystrophy
---- True hypoparathyrodism.
— Tumour Lysis syndrome.
* Vit. D Deficiency — causes  low or normal level of calcium and phosphate
* Severe Magnesium deficiency is associated with hypocalcemia. Theeffect of Mg on PTH secretion is similar to Ca2+ but of little significance because, calcium effectspredominate. Again, it is found that severe Mg deficiency associated with blunted secretion of PTH.

Phosphate level is not elevated in hypomagnesemia, as phosphate deficiency is frequent accompaniment of hypomagnesemia.