Management of choice for endometrial cancer (in post-menopausal female) is:
A. Chemotherapy
B. Cone biopsy
C. Dilation and curettage
D. Hysterectomy
Ans.
D.
Endometrial cancer is the most
common gynecologic cancer in women ages 45 and older. The main factor
that predisposes a woman to the development of endometrial cancer is exposure
to unopposed estrogen, whether endogenous or exogenous. Endogenous factors
include, early menarche, late menopause, chronic anovulation,
estrogen-secreting ovarian tumors, and obesity. Exogenous factors include the
ingestion of unopposed estrogen (as with estrogen replacement therapy). Hypertension
and diabetes have also been associated with endometrial cancer, though this
relationship may likely be related to obesity.
The current
accepted management protocol for endometrial cancer (based on endometrial
biopsy report) is total abdominal hysterectomy, bilateral adnexectomy, and
possible lymph node sampling.
