Which of the following streptococcal components cross reacts to synovium of human tissues?
A. Carbohydrate C antigenB. Polysaccharide capsule
C. Capsular hyaluronic acid
D. Cell wall antigen
Ans. C. (Capsular hyaluronic acid)
Explanation
Various structural components of Streptococcus pyogenes exhibit antigenic cross-reaction with different tissues of the human body. Antigenic relationships have been demonstrated between:
a. Capsular hyaluronic acid and human synovial fluid
b. Cell wall protein and myocardium
c. Group A carbohydrate and cardiac valves
d. Cytoplasmic membrane antigens and vascular intima and
e. Peptidoglycan and skin antigens
