Which of the following is not a feature of Stauffer syndrome?
A. Erythrocytosis
B. Hypercalcemia C. Metastatic hepatic dysfunction
D. Dysfibrinogenemia
Correct Ans.
C. Metastatic hepatic dysfunction
A spectrum of paraneoplastic syndromes
has been associated with these malignancies, including erythrocytosis,
hypercalcemia, nonmetastatic hepatic dysfunction Stauffer syndrome. , and
acquired dysfibrinogenemia.
Stauffer syndrome is a constellation of
signs and symptoms of liver dysfunction that arise due to presence of renal
cell carcinoma but are not due to tumour infiltration into the liver and/or
intrinsic liver disease; it is a paraneoplastic syndrome.
It leads to elevated liver function
tests, which results from cholestasis, i.e. a cessation of bile flow. The
symptoms resolve if the renal cell cancer is successfully treated.
