True about PNH MCQ | PGI MCQs for MD MS Preparations

True about PNH is/are :

A. Hypocellular marrow
B. Budd-chairi syndrome 
C. Thrombosis
D. LAP Score low
E. Polycythemia

Ans. B. Budd-chiari syndrome; (C) Thrombosis;(D) LAP Score low

• Three common manifestations of PNH 

— Hemolytic anemia (intravascular) 

— Venous thrombosis 

— Deficient haematopoiesis (pancytopenia) 

•Bone marrow appears normocellular but in vitro marrow progenitor areabnormal in PNH. 

• Budd-chiari syndrome is hepatic vein thrombosis can occur in PNH. 

• LAP score is low.