Two specific tests to diagnose wilson’s disease are:
A. KF ring
B. Liver copper by dry weight of liver < 200 microgm/gm of dry weight
C. Sr. Ceruloplasmin
D. 24 hours urine copper after penicillamine
E. Sr. copper
A. KF ring
B. Liver copper by dry weight of liver < 200 microgm/gm of dry weight
C. Sr. Ceruloplasmin
D. 24 hours urine copper after penicillamine
E. Sr. copper
Ans. A. KF ring ; (C) Sr. Ceruloplasmin
The
diagnosis of wilson’s disease is confirmed by demonstration of either
(i)
Sr. Ceruloplasmin level <20
mg/dl and K.F. ring QI
(ii) Serum ceruloplasmin level <20 mg/dl and a concentration of copper
in a liver biopsy sample >200
microgm/gm dry weight.
In the question, mentioned copper concentration 200 µgm/g dry wt. So, combined
A, C will be the best choice.
