Acute viral hepatitis | PGIMER MCQs

Acute viral hepatitis is characterized by 

A. Piece meal necrosis 
B. Zonal necrosis 
C. Focal necrotic spot 
D. Liver is enlarged and bile stained 
E. Bridging necrosis.

Ans. B. Zonal necrosis ; (C) Focal necrotic spot ; (D) Liver enlarged with bile stained 

— In acute viral hepatitis, liver is slightly enlarged, soft and greenish. Following pathologic changes are seen:-

— Ballooning degeration of hepatocytes.

— Some hepatocytes become necrotic and forms eosinophilic councilman body or acidophilic body.

—Dropout necrosis, where some hepatocytes undergo lysis. 

Focal necrosis; this type of necrosis involves small group of hepatocytes irregularly distributed in hepatic lobules. Piece meal necrosis and bridging necrosis is seen in chronic active hepatitis.