Levosulpiride acts as antagonist of which central dopamine receptor?
A. D2
B. 03
C. 04
D. All of the above
Ans.
D. All of the above
A substituted benzamide anti-psychotic,
reported to be a selective antagonist of central dopamine D-2, D-3 and
D-4. receptors, Levosulpiride is also
claimed to have mood elevating properties. Levosulpiride is used in the
treatment of psychoses, particularly negative symptoms of schizophrenia,
anxiety disorders, dysthymia, vertigo, dyspepsia, irritable bowel syndrome and
premature ejaculation.
In a dose range of 50-200 mg/day,
Levosulpiride is therapeutic for negative and cognitive symptoms of
schizophrenia, and for depressive and somatoform disorders
