Causes of eosinophilia | Frequently Asked MCQ Topics

All of the following are causes of eosinophilia except:

A. Hodgkin’s disease 
B. Filariasis
C. MI 
D. HIV infection

Ans. C.

• Conditions producing allergic reactions & resulting eosinophilia are: 

* Drugs: Iodides, Aspirin, Sulfonamides, Nitrofurantoin, Penicillin, Cephalosporins. 

* Disease conditions : Hay fever, Asthma, Eczema, Serum sickness, Allergic vasculitis, Pemphigus. 

* All types of parasitic infection. 

* Collagen vascular disease : RA, Eosinophillic fasciitis, Allergic angiitis, Polyarteritis nodosa. 

* Malignancy : Hodgkins disease, Mycosis fungoides, CML, Ca stomach, ovary, lung, pancreas 

and uterus. 

* Other diseases Job’s syndrome, Sarcoidosis, Skin disease. 

* Viral infection like HIV and human T-cell lymphotropic virus HTLV-1.  

* In MI polymorphonuclear leukocytosis seen.

* Most dramatic hypereosinophilia syndromes are eosinophil count 50,000 to 1,00,000/pA.  

- Loeffler’s syndrome 

- Tropical pulmonary eosinophlllia 

- Loeffler’s endocarditis 

- Eosinophilic leukaemia 

- Idiopathic hypereosinophillic syndrome. 

* In eosinophilia, eosinophil count>500

* Eosinopenia seen in 

- Stress 

- Acute bacterial infection 

- After Rx of glucocorticoids.