Content of Aschotf’s nodules are All Except
a. Histiocytesb. Langhan’s giant cell
c. Fibrinoid deposition
d. Aschoft’s cells
e. Lumbar bodies
Ans. is b and e. i.e. Langhan’s giant cell and Lumbar bodies
• Aschoff bodies
are diagnostic of rheumatic fever.
• Aschoff bodies constitute:
— Fibrinoid degeneration (necrosis).
— Fibrinoid necrosis is surrounded by T-cells, plasma cells,
plump macrophages called Anitschkow cells (pathognomonic of RE).
• These are distinctive cells have abundant amorphous cytoplasm and central round to ovoid nuclei in central, slender, wavy ribbon (hence designation, caterpillar cells).
• These are distinctive cells have abundant amorphous cytoplasm and central round to ovoid nuclei in central, slender, wavy ribbon (hence designation, caterpillar cells).
• Some of the larger macrophages
