Which of the following is true regarding exotoxin?
A. They are very stable and resist most physical and chemical agentsB. Highly antigenic
C. Produced abundantly by gram negative bacilli
D. Lipopolysaccharide-protein complex in nature
Ans. B. Highly antigenic
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Endotoxin
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Exotoxin
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Liberated after cell disintegration
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Excreted by living cells
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Lipolysaccharide LPS. -protein complex
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Proteins with molecular weight 70,000 —
1,00,000.
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Heat stable
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Heat labile and lose their toxicity on exposure
to 60 degree centigrade. Only exception is enterotoxin of Staphylococcus
aureus
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Can not be
converted to toxoid
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Can be converted to toxoid
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Nonspecific in action
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Highly specific in action
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Weakly toxic
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Highly toxic substances
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Poorely antigenic
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Highly antigenic
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Produced by gram
negative bacteria
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Produced by gram positive and negative bacteria
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