Which statement regarding serologic diagnosis of infections mononucleosis is correct?
A. A heterophile. antibody is formed that reacts with the membrane protein of EBV.B. A heterophile antibody is formed that agglutinates sheep or horse red blood cells.
C. A heterophile antigen occurs that cross-reacts with atypical lymphocytes.
D. A heterophile antigen occurs following infection with both EBV and CMV
Ans. B. A heterophile antibody is formed that agglutinates
sheep or horse red blood cells.
A
nonspecific heterophile agglutination test Monospot test. is commercially available and can be used to diagnose EBV infectious mononucleosis
within a week to months of infection. Infectious mononucleosis-like
infection caused by CMV is heterophile negative.
