The most common presentation of neuroblastoma in children is:
B. Lung metastasis
C. Renal invasion
D. Secondaries in the brain
Ans. A. [Lytic lesion in the skull with suture diathesis]
Neuroblastoma
- Tumor metastasize very early to bone lymph nodes, liver, subcutaneous tissue
and the bone marrow metastasis may be the first manifestation of the tumor
•Orbital
proptosis, ° spinal cord compression or fever and bone pain may be the
earliest manifestations
•The
most common symptom is pain from primary or metastatic.
•
Neuroblastoma is the most common abdominal tumor to demonstrate
cetciticetions" 50%. Prior
to chemotherapy
•Most
neuroblastoma are radiosensitive and respond to 3000 cGY or less of radiation
•Infiltration
of the sutures - translucencies in skull vault and 'sun ray' spiculation a
reaction to sub pericranial deposits. .
