Wednesday, 9 December 2015

Medical PG Preparations | Lipid lowering agent


Which of the following is not an action of lipid lowering agent?

A. Decreased hepatic cholesterol synthesis 
B. Decreased LDL receptors 
C. Inhibiting HMG-CoA reductase
D. Decreasing VLDL

Ans. B. Decreased LDL receptors.  
Explanation: LDL receptor expression increases. This occurs due to inhibition of cholesterol synthesis in liver. Therefore, liver has to transport cholesterol from periphery. To receive large amount of cholesterol, liver synthesizes receptors for LDL