Wednesday, 9 December 2015

PGIMER Frequently Asked Medical PG topics | Painful lymphadenopathy


Painful lymphadenopathy is seen in: 

A. Donovanosis 
B. Syphilis 
C. Chancroid 
D. Herpes simplex 
E. Gonorrhaea


Ans. (C) Chancroid (D)Herpes Simplex :
• The lymph nodes are painful in both acute and chronic lymphadenitis acute leukemia, but are painless in syphillis, lymphosarcoma, secondary carcinoma, lymphoma etc. 
Chancroid (Soft chancre)is caused by Haemophilus Ducreyi, has an IP of 3-5 days is characterised by painful, non indurated ulcer and painful lymphadenopathy. Ito test is done here. 
• Donovanosis or granuloma inguinale is caused by calymmatobacterium granulomatis, has an IP of 1-4 wks in characterised by one or more subcutaneous nodules that erode through skin to produce ulcer, granulomatous sharply defined painless leson. The genitalia are involved in 90% of cases and genital swelling, particularly of the labia, is a common feature and occasionally progresses to psuedoelephastiasis. Lymphadeopathy is not seen and pseudobubos are seen.

• In syphilis, painless, indurated papule formed that may turn to ulcer and painless, firm, shotty, discrete lymphadenophthy is seen.
• In herpes infection, painful papule is formed that ulcerate in 3-6 days. Tender inguinal lymphadenopathy dysuria, urethral and vaginal discharge are local Sx. 
•In Gonorrhea, lymphadenopathy is not found. 
In lymphogranuloma venerum after the genital lesion has healed, painful matted suppurative lymphadenopathy occurs. Multiple sinus tracts, Groove’s sign.Elephantiasis of valve positive.
Frei’s intradermal test is positive.