Tuesday 15 December 2015

State Medical PG Entrance | Beta-endorphin


Which statement about beta-endorphin is most accurate? 

A. It is exclusively located in the spinal cord 
B. Enzymes for its synthesis are located in nerve endings 
C. It selectively activates delta opioid receptors 
D. Its actions are mainly inhibitory

Ans. D.  Its actions are mainly inhibitory
The opioid peptides are widely distributed in the CNS at all levels of the neuraxis and are synthesized in the cell bodies.

They activate several receptor subtypes and cause inhibition. No mechanism has been described for termination of the synaptic actions of endogenous peptides