Which of the following soft tissue tumors is chemo resistant?
A. Synovial sarcoma
B. Osteosarcoma
C. Malignant fibrous histiocytoma
D. Alveolar cell carcinoma
A. Synovial sarcoma
B. Osteosarcoma
C. Malignant fibrous histiocytoma
D. Alveolar cell carcinoma
Ans. D.
Alveolar cell carcinoma
Synovial
sarcoma: wide resection + chemo + radiaiton Osteosarcoma:
Pre-op chemo " surgery " Post-op chemo Malignant
fibrous histiocytoma: wide resection + adjuvant chemo ± radiation Non-small cell carcinomas epidermoid, adenocarcinomas, large cell Ca, bronchoalveolar carcinomas, and mixed version
do not respond well to chemotherapy as small cell cancers.